The health
maintenance system is founded on the balance of
androgens
(included precursors and derived from Testosterone)
It is the study of individual biochemistry which guides the
treatment because each one ages at its manner. The biochemical
study makes
it possible to determine the amount necessary to take,
according to the quantity of missing hormone and according
interactions that this treatment will start on secretion of
the other hormones.
This page develops in short some current knowledge on
the hormonal "anti aging" treatment “. Let us see initially
some principles on DHEA, growth hormone (GH), thyroxin and
cortisone.
WARNING
:
When there is no symtom there is no disease and if there
is no disease a hormonal treatment is not necessary
DHEA
DHEA has no sexual effect
DHEA is not a hormone. The hormonal receptor of
DHEA was never shown.
DHEA is a biochemical precursor of testosterone (of
which the cellular receptor is universal).This
transformation into testosterone is realizable only
by a specific
enzymatic path in
the cells that “produce” testosterone.
The introduced DHEA in the organism is transformed a little
into testosterone but especially into “androsterone” which
has light androgenic properties.
The introduced DHEA is also transformed into a series of
biochemical components.
The use of the DHEA will never replace the effect of the
“finished” hormone, the testosterone.
The DHEA is not a “mysterious hormone”. It is a natural
molecule, as sugar. Its molecular composition is known since
its discovery by Butenandt in 1936 which received the Nobel
Prize for this discovery which led to the synthesis of
testosterone.
The DHEA does not have any sexual action in man.
There exist counter-indications for DHEA (breast cancer,
pregnancy, prostate problems )
Prescribing a standard daily dose of 50 or 25 milligrams
acts against all senses and is a negative direction. Any
treatment must be adapted. 10 milligrams of DHEA per day is
already much.
As the DHEA is transformed into many distinct chemical
components, it is necessary to check these various
transformations by checking these chemical molecules not
only in blood but
also
their metabolites in the urine.
. Simple
blood tests for DHEA are not enough to understand the
control of the treatment.
In the Nineties certain authors wonder whether the DHEA was
not the Fountain of Youth? iN
2003 a
scientific publication (followed by others) wonders: “Is
the Fountain of Youth dried up?” (download).
Growth hormone (GH) (is
not an anti aging treatment ! Be prudent!)
There exist dwarves centenaries (who
do not secrete growth hormone) whereas giants (who secrete
too much growth hormone) do not exceed fifty years.
Very recent studies show the negative
effect of
the growth hormone on longevity:
GH is oxidative.pdf :The
growth hormone causes an oxidative stress.
GH
and cardiac disease.pdf: It
is not proven that the administration of growth hormone is
favorable at the cardiac one.
GH and higher mortality.pdf: The
administration of growth hormone accelerates the mortality
of the very ill patients.
http://georgesdebled.org/GH Somatopause to treat or not.pdf:
The treatment by the growth hormone is not founded.
2007 -
Patients with congenital deficiency of IGF-I
seem protected from
the development of malignancies: a preliminary report : IGF1,
growth factor, is stimulated by GH (growth hormone) which
consequently enhances cancer growth.
2008 - Longevity
is linked with receptor's resistance to the growth factor
IGF1 This
finding implicates a negative
effect of
Growth hormone on longevity !
A
dministration
of growth hormone can be advised only after having practiced
a specific biological clarification and functional
specific tests to practice preferably in department of
endocrinology. Administration of growth hormone cannot be
made in a random way, as it is too often seen (even under
the pretext of administrate small amounts)
Thyroxin
The administration of this hormone is indicated only in
hypothyroidism which is a well-known disease.
A
treatment is not justified in absence of specific
symptoms.
Cortisone
The administration of this hormone is indicated only in the
shown hormonal insufficiencies.
A
treatment is not justified in absence of specific
symptoms.
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